Leuk Lymphoma. 2021 Jul 19:1-12. doi: 10.1080/10428194.2021.1953006. Online ahead of print. ABSTRACT Treatment of pediatric acute lymphoblastic leukemia (ALL) with pegaspargase exploits ALL cells dependency on asparagine. Pegaspargase depletes asparagine, consequentially affecting aspartate, glutamine and glutamate. The gut as a confounding source of these amino acids (AAs) and the role of gut microbiome metabolism of …
July 2021 archive
Jul 14
Development of a free radical scavenging bacterial consortium to mitigate oxidative stress in cnidarians
Corals are colonized by symbiotic microorganisms that profoundly influence the animal’s health. One noted symbiont is a single-celled alga (in the dinoflagellate family Symbiodiniaceae), which provides the coral with most of its fixed carbon. Thermal stress increases the production of reactive oxygen species (ROS) by Symbiodiniaceae during photosynthesis. ROS can both damage the algal symbiont’s photosynthetic machinery and inhibit its repair, causing a positive feedback loop for the toxic…
Jul 07
Correction to: A multi-OMIC characterisation of biodegradation and microbial community succession within the PET plastisphere
Microbiome. 2021 Jul 6;9(1):155. doi: 10.1186/s40168-021-01120-y. NO ABSTRACT PMID:34229759 | DOI:10.1186/s40168-021-01120-y
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