Claudio Slamovits

Author's posts

N-Linked Surface Glycan Biosynthesis, Composition, Inhibition, and Function in Cnidarian-Dinoflagellate Symbiosis

The success of symbioses between cnidarian hosts (e.g., corals and sea anemones) and micro-algal symbionts hinges on the molecular interactions that govern the establishment and maintenance of intracellular mutualisms. As a fundamental component of innate immunity, glycan-lectin interactions impact the onset of marine endosymbioses, but our understanding of the effects of cell surface glycome composition on symbiosis establishment remains limited. In this study, we examined the canonical…

Bacterial Taxa and Functions Are Predictive of Sustained Remission Following Exclusive Enteral Nutrition in Pediatric Crohn’s Disease.

Related Articles Bacterial Taxa and Functions Are Predictive of Sustained Remission Following Exclusive Enteral Nutrition in Pediatric Crohn’s Disease. Inflamm Bowel Dis. 2020 Jan 21;: Authors: Jones CMA, Connors J, Dunn KA, Bielawski JP, Comeau AM, Langille MGI, Van Limbergen J Abstract BACKGROUND: The gut microbiome is extensively involved in induction of remission in pediatric …

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Piece by Piece: Building a Ribozyme.

Related Articles Piece by Piece: Building a Ribozyme. J Biol Chem. 2020 Jan 17;: Authors: Gray MW, Gopalan V Abstract The ribosome and ribonuclease P (RNase P) are cellular ribonucleoprotein complexes that perform peptide bond synthesis and phosphodiester bond cleavage, respectively. Both are ancient biological assemblies that were already present in the last universal common …

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Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii.

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Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii.
Microorganisms. 2020 Jan 11;8(1):
Authors: Li T, Yu L, Song B, Song Y, Li L, Lin X, Lin S
Abstract
Cataloging a…

Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii

Cataloging an accurate functional gene set for the Symbiodiniaceae species is crucial for addressing biological questions of dinoflagellate symbiosis with corals and other invertebrates. To improve the gene models of Fugacium kawagutii, we conducted high-throughput chromosome conformation capture (Hi-C) for the genome and Illumina combined with PacBio sequencing for the transcriptome to achieve a new genome assembly and gene prediction. A 0.937-Gbp assembly of F. kawagutii were obtained, with a…

The role of chromatin dynamics under global warming response in the symbiotic coral model Aiptasia.

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The role of chromatin dynamics under global warming response in the symbiotic coral model Aiptasia.
Commun Biol. 2019 Aug 02;2(1):282
Authors: Weizman E, Levy O
Abstract
Extreme weat…

Comparative plastid genomics of Cryptomonas species reveals fine-scale genomic responses to loss of photosynthesis.

Related Articles Comparative plastid genomics of Cryptomonas species reveals fine-scale genomic responses to loss of photosynthesis. Genome Biol Evol. 2020 Jan 10;: Authors: Tanifuji G, Kamikawa R, Moore CE, Mills T, Onodera NT, Kashiyama Y, Archibald JM, Inagaki Y, Hashimoto T Abstract Loss of photosynthesis is a recurring theme in eukaryotic evolution. In organisms that …

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Supramolecular multilayer organization of chromosomes: possible functional roles of planar chromatin in gene expression and DNA replication and repair.

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Supramolecular multilayer organization of chromosomes: possible functional roles of planar chromatin in gene expression and DNA replication and repair.
FEBS Lett. 2019 Dec 27;:
Authors: Daban JR

Supramolecular multilayer organization of chromosomes: possible functional roles of planar chromatin in gene expression and DNA replication and repair

Experimental evidence indicates that the chromatin filament is self-organized into a multilayer planar structure that is densely stacked in metaphase and unstacked in interphase. This chromatin organization is unexpected, but it is shown that diverse supramolecular assemblies, including dinoflagellate chromosomes, are multilayered. The mechanical strength of planar chromatin protects the genome integrity, even when double-strand breaks are produced. Here, it is hypothesized that the chromatin…

Genome-Wide Identification and Characterization of SODs in Zhikong Scallop Reveals Gene Expansion and Regulation Divergence after Toxic Dinoflagellate Exposure.

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Genome-Wide Identification and Characterization of SODs in Zhikong Scallop Reveals Gene Expansion and Regulation Divergence after Toxic Dinoflagellate Exposure.
Mar Drugs. 2019 Dec 12;17(12):
Authors…