Dinoflagellates have some of the largest genomes, and their liquid-crystalline chromosomes (LCCs) have high degrees of non-nucleosomal superhelicity with cation-mediated DNA condensation. It is currently unknown if condensins, pentameric protein complexes containing structural maintenance of chromosomes 2/4, commonly involved in eukaryotic chromosomes condensation in preparation for M phase, may be involved in the LCC structure. We find that CcSMC4p (dinoflagellate SMC4 homolog) level peaked at…
April 2020 archive
Apr 17
Publisher Correction: Genetic tool development in marine protists: emerging model organisms for experimental cell biology
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Apr 16
Transcriptomic analysis of polyketide synthases in a highly ciguatoxic dinoflagellate, Gambierdiscus polynesiensis and low toxicity Gambierdiscus pacificus, from French Polynesia
Marine dinoflagellates produce a diversity of polyketide toxins that are accumulated in marine food webs and are responsible for a variety of seafood poisonings. Reef-associated dinoflagellates of the genus Gambierdiscus produce toxins responsible for ciguatera poisoning (CP), which causes over 50,000 cases of illness annually worldwide. The biosynthetic machinery for dinoflagellate polyketides remains poorly understood. Recent transcriptomic and genomic sequencing projects have revealed the…
Apr 08
Genetic tool development in marine protists: emerging model organisms for experimental cell biology.
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Genetic tool development in marine protists: emerging model organisms for experimental cell biology.
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Apr 07
Genetic tool development in marine protists: emerging model organisms for experimental cell biology
Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represent eukaryotic diversity or environmentally relevant taxa. Here, we report on the development of genetic tools in a range of protists primarily from marine environments. We present evidence for foreign DNA delivery and expression in 13 species never…
Apr 06
Genetic tool development in marine protists: emerging model organisms for experimental cell biology
Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represent eukaryotic diversity or environmentally relevant taxa. Here, we report on the development of genetic tools in …
Apr 03
Getting clear about the F-word in genomics.
Related Articles Getting clear about the F-word in genomics. PLoS Genet. 2020 Apr 01;16(4):e1008702 Authors: Linquist S, Doolittle WF, Palazzo AF PMID: 32236092 [PubMed – as supplied by publisher]
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