Category: Papers by CGEB labs

A phenotype-genotype codon model for detecting adaptive evolution.

Related Articles A phenotype-genotype codon model for detecting adaptive evolution. Syst Biol. 2019 Nov 15;: Authors: Jones CT, Youssef N, Susko E, Bielawski JP Abstract A central objective in biology is to link adaptive evolution in a gene to structural and/or functional phenotypic novelties. Yet most analytic methods make inferences mainly from either phenotypic data …

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Genome-wide Transcriptional Analysis of Tetrahymena thermophila Response to Exogenous Cholesterol.

Related Articles Genome-wide Transcriptional Analysis of Tetrahymena thermophila Response to Exogenous Cholesterol. J Eukaryot Microbiol. 2019 Nov 09;: Authors: Najle SR, Hernández J, Ocaña-Pallarès E, García Siburu N, Nusblat AD, Nudel CB, Slamovits CH, Uttaro AD Abstract The ciliate Tetrahymena thermophila does not require sterols for growth and synthesizes pentacyclic triterpenoid alcohols, mainly tetrahymanol, as …

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CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database.

Related Articles CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database. Nucleic Acids Res. 2019 Oct 29;: Authors: Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen AV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran HK, Werfalli RE, Nasir JA, Oloni M, Speicher DJ, Florescu …

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The New Tree of Eukaryotes.

Related Articles The New Tree of Eukaryotes. Trends Ecol Evol. 2019 Oct 09;: Authors: Burki F, Roger AJ, Brown MW, Simpson AGB Abstract For 15 years, the eukaryote Tree of Life (eToL) has been divided into five to eight major groupings, known as ‘supergroups’. However, the tree has been profoundly rearranged during this time. The …

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Evolution: New Protist Predators under the Sun.

Related Articles Evolution: New Protist Predators under the Sun. Curr Biol. 2019 Oct 07;29(19):R936-R938 Authors: Colp MJ, Archibald JM Abstract A lineage of predatory, non-photosynthetic protists related to red algae has been discovered, changing the way we think about the biology of the first photosynthetic eukaryotes. PMID: 31593671 [PubMed – in process]

A single-cell genome reveals diplonemid-like ancestry of kinetoplastid mitochondrial gene structure.

Related Articles A single-cell genome reveals diplonemid-like ancestry of kinetoplastid mitochondrial gene structure. Philos Trans R Soc Lond B Biol Sci. 2019 Nov 25;374(1786):20190100 Authors: Wideman JG, Lax G, Leonard G, Milner DS, Rodríguez-Martínez R, Simpson AGB, Richards TA Abstract Euglenozoa comprises euglenids, kinetoplastids, and diplonemids, with each group exhibiting different and highly unusual mitochondrial …

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Combined cultivation and single-cell approaches to the phylogenomics of nucleariid amoebae, close relatives of fungi.

Related Articles Combined cultivation and single-cell approaches to the phylogenomics of nucleariid amoebae, close relatives of fungi. Philos Trans R Soc Lond B Biol Sci. 2019 Nov 25;374(1786):20190094 Authors: Galindo LJ, Torruella G, Moreira D, Eglit Y, Simpson AGB, Völcker E, Clauß S, López-García P Abstract Nucleariid amoebae (Opisthokonta) have been known since the nineteenth …

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Neutral evolution of cellular phenotypes.

Neutral evolution of cellular phenotypes. Curr Opin Genet Dev. 2019 Sep 28;58-59:87-94 Authors: Wideman JG, Novick A, Muñoz-Gómez SA, Doolittle WF Abstract Eukaryotes exhibit a great diversity of cellular and subcellular morphologies, but their basic underlying architecture is fairly constant. All have a nucleus, Golgi, cytoskeleton, plasma membrane, vesicles, ribosomes, and all known lineages but …

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Current and Promising Approaches to Identify Horizontal Gene Transfer Events in Metagenomes.

Related Articles Current and Promising Approaches to Identify Horizontal Gene Transfer Events in Metagenomes. Genome Biol Evol. 2019 Aug 26;: Authors: Douglas GM, Langille MGI Abstract High-throughput shotgun metagenomics sequencing has enabled the profiling of myriad natural communities. This data is commonly used to identify gene families and pathways that were potentially gained or lost …

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Ecological and evolutionary patterns in the enigmatic protist genus Percolomonas (Heterolobosea; Discoba) from diverse habitats.

Related Articles Ecological and evolutionary patterns in the enigmatic protist genus Percolomonas (Heterolobosea; Discoba) from diverse habitats. PLoS One. 2019;14(8):e0216188 Authors: Tikhonenkov DV, Jhin SH, Eglit Y, Miller K, Plotnikov A, Simpson AGB, Park JS Abstract The heterotrophic flagellate Percolomonas cosmopolitus (Heterolobosea) is often observed in saline habitats worldwide, from coastal waters to saturated brines. …

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